Rekombinanter MAPT Antikörper (pThr231)
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- Target Alle MAPT Antikörper anzeigen
- MAPT (Microtubule-Associated Protein tau (MAPT))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- pThr231
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser MAPT Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Phospho-MAPT (T231)
- Klon
- 1G9
- Isotyp
- IgG
- Top Product
- Discover our top product MAPT Primärantikörper
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- Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MAPT (Microtubule-Associated Protein tau (MAPT))
- Andere Bezeichnung
- MAPT (MAPT Produkte)
- Hintergrund
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Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
Aliases: Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU
- UniProt
- P10636
- Pathways
- MAPK Signalweg, Microtubule Dynamics, M Phase, Regulation of Cell Size
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