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Rekombinanter MGMT Antikörper

MGMT Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Monoclonal 10G7 unconjugated Recombinant Antibody
Produktnummer ABIN7127619
  • Target Alle MGMT Antikörper anzeigen
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 74
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 12
    Kaninchen
    Klonalität
    • 62
    • 19
    Monoklonal
    Konjugat
    • 46
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MGMT Antikörper ist unkonjugiert
    Applikation
    • 56
    • 32
    • 22
    • 21
    • 14
    • 13
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human MGMT
    Klon
    10G7
    Isotyp
    IgG
    Top Product
    Discover our top product MGMT Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Andere Bezeichnung
    MGMT (MGMT Produkte)
    Synonyme
    AGT antikoerper, AI267024 antikoerper, Agat antikoerper, O-6-methylguanine-DNA methyltransferase antikoerper, MGMT antikoerper, Mgmt antikoerper
    Hintergrund

    Background: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

    Aliases: Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (MGMT) (O-6-methylguanine-DNA-alkyltransferase), MGMT

    UniProt
    P16455
    Pathways
    DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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