Rekombinanter GZMB Antikörper
Kurzübersicht für Rekombinanter GZMB Antikörper (ABIN7127523)
Target
Alle GZMB Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Granzyme B
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Isotyp
- IgG
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human IHC, StM Wirt: Maus Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 4E4 unconjugated
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Applikationshinweise
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- GZMB
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Hintergrund
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Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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