Rekombinanter BMI1 Antikörper
Kurzübersicht für Rekombinanter BMI1 Antikörper (ABIN7127369)
Target
Alle BMI1 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Bmi1
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))
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Andere Bezeichnung
- BMI1
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Hintergrund
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Background: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Aliases: Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51), BMI1, PCGF4 RNF51
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UniProt
- P35226
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Pathways
- Zellzyklus, Autophagie
Target
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