Rekombinanter APC Antikörper
Kurzübersicht für Rekombinanter APC Antikörper (ABIN7127341)
Target
Alle APC Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- APC Recombinant Monoclonal Antibody
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human APC
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Isotyp
- IgG
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anti-Adenomatous Polyposis Coli (APC) (AA 2636-2845) antibody
APC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2544-2843) antibodyAPC Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2634-2842) antibodyAPC Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (pSer2054) antibodyAPC Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2744-2843) antibodyAPC Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 3E2 unconjugated
anti-Adenomatous Polyposis Coli (APC) (C-Term) antibodyAPC Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) (AA 2751-2843) antibodyAPC Reaktivität: Ratte ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Adenomatous Polyposis Coli (APC) antibodyAPC Reaktivität: Human, Maus, Ratte IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB:1:500-1:5000, IHC:1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- APC (Adenomatous Polyposis Coli (APC))
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Andere Bezeichnung
- APC
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Hintergrund
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Background: Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization.
Aliases: Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5), APC, DP2.5
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UniProt
- P25054
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Pathways
- WNT Signalweg, Stem Cell Maintenance, Cell-Cell Junction Organization
Target
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