PSMD4/ASF Antikörper

Produktnummer ABIN7126850

Produktdetails anti-PSMD4/ASF Antikörper

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PSMD4/ASF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: In eukaryotic cells, selective breakdown of cellular proteins is ensured by two distinct pathways. First, appropriate proteins are tagged for degradation by ubiquitination. Second, these multiubiquitinated proteins are degraded by the highly selective 26S Proteasome protein-destroying machinery. At specific stages of development, embryo- and tissue-specific components of the 26S Proteasome are formed, which are termed Rpn10a through Rpn10e, or alternatively pUb-R2 through pUb-R5. All members of this family can be generated by a single Rpn10 gene by developmentally regulated alternative splicing. The pUb-R2 subunit, originally identified as S5a (also designated antisecretory factor and multiubiquitin chain binding protein) is ubiquitously expressed and may perform proteolysis constitutively in a wide variety of cells. pUb-R4 and pUb-R5 may have embryo- or tissue-specific expression and may play specialized roles in early embryonic development.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human PSMD4protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat or HepG2 cells. Liver tissue lysate. Human liver, tonsil or kidney.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu PSMD4/ASF

Target: PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))

Andere Bezeichnung: PSMD4 (Psmd4 Produkte)

Synonyme: af-1 antikoerper, mcb1 antikoerper, pub-r5 antikoerper, rpn10 antikoerper, PSMD4 antikoerper, DDBDRAFT_0202512 antikoerper, DDBDRAFT_0232981 antikoerper, DDB_0202512 antikoerper, DDB_0232981 antikoerper, AF antikoerper, AF-1 antikoerper, ASF antikoerper, MCB1 antikoerper, Rpn10 antikoerper, S5A antikoerper, pUB-R5 antikoerper, xrpn10c antikoerper, Af1 antikoerper, Mcb1 antikoerper, angiocidin antikoerper, im:6912672 antikoerper, psmd4 antikoerper, wu:fc68c04 antikoerper, zgc:110247 antikoerper, proteasome 26S subunit, non-ATPase 4 antikoerper, 26S proteasome non-ATPase regulatory subunit 4 antikoerper, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antikoerper, proteasome 26S subunit, non-ATPase 4 L homeolog antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antikoerper, proteasome 26S subunit, non-ATPase 4b antikoerper, psmd4 antikoerper, PSMD4 antikoerper, LOC100194679 antikoerper, psmD4 antikoerper, LOC100283637 antikoerper, Smp_000740.1 antikoerper, psmd4.L antikoerper, Psmd4 antikoerper, psmd4b antikoerper

Hintergrund: 26S proteasome non-ATPase regulatory subunit 4, 26S proteasome regulatory subunit RPN10, 26S proteasome regulatory subunit S5A, AF, AF-1,26S proteasome non-ATPase regulatory subunit 4
Cellular localisation: Nucleus and cytoplasm.

Molekulargewicht: 50kDa

Gen-ID: 5710, 505059

UniProt: P55036

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway