Galectin 3 Antikörper (AA 150-200)

Produktnummer ABIN7126640

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Galectin 3 in IHC (f). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Galectin 3 Antikörper (AA 150-200) (ABIN7126640)

Target: Galectin 3 (LGALS3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Produktdetails anti-Galectin 3 Antikörper

Bindungsspezifität: AA 150-200

Spezifität: Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid.Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiationof benign and malignant thyroid neoplasms.Galectin-3 may also be useful in the identification of certain liver disorders.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A synthetic peptide from the C-terminus of human LGALS3protein (aa 150-200) (exact sequence is proprietary)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human papillary thyroid carcinoma tissue.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: LGALS3

Substanzklasse: Chemical

Hintergrund: 35 kDa lectin, Carbohydrate-binding protein 35, CBP35, Gal-3, GAL3, Galactose-specific lectin 3, GALBP, Galectin-3, GALIG, GBP, IgE-binding protein, L-34 galactoside-binding lectin, L31, Laminin-binding protein, Lectin L-29, Lectin, galactose binding, soluble 3, LGALS2, LGALS3, MAC2, Macrophage galactose-specific lectin,Galectin-3 (LGALS3) (Thyroid Cell Marker)
Cellular localisation: Cytoplasm.

Molekulargewicht: 30kDa

Gen-ID: 3958, 531081

UniProt: P17931

Pathways: RTK Signalweg