Rekombinanter KRT6A Antikörper

Produktnummer ABIN7126617

Der Kaninchen Monoklonal anti-KRT6A Antikörper wird verwendet zum Nachweis von KRT6A in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Rekombinanter KRT6A Antikörper (ABIN7126617)

Target: KRT6A (Keratin 6A (KRT6A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: KRT6-3997R

Produktdetails anti-KRT6A Antikörper

Verwendungszweck: Recombinant Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody

Spezifität: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16.Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests.Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human KRT6 (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Human tonsil or basal cell carcinoma (BCC).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: KRT6A

Hintergrund:

CK6A, CK6B, CK6C, CK6D, CK6E, Keratin Type II Cytoskeletal 6A, Keratin Type II Cytoskeletal 6B, Keratin Type II

HeLa cells. Human tonsil or basal cell carcinoma (BCC).

Molekulargewicht: 56kDa

Gen-ID: 3853, 700779

UniProt: P02538