IL3RA Antikörper (AA 26-171)

Produktnummer ABIN7126575

Der Maus Monoklonal Anti-IL3RA-Antikörper wurde für ELISA und Coat validiert. Er ist geeignet, IL3RA in Proben von Human zu detektieren.

Kurzübersicht für IL3RA Antikörper (AA 26-171) (ABIN7126575)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Produktdetails anti-IL3RA Antikörper

Bindungsspezifität: AA 26-171

Spezifität: CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human IL3RA protein fragment (around aa 26-171) (exact sequence is proprietary)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), ,Optimal dilution for a specific application should be determined.

Positive_Control: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: IL3RA

Hintergrund: CD123, hIL3Ra, IL-3R-alpha, IL-3RA, IL3RAX, IL3RAY, IL3RX, IL3RY, Interleukin-3 Receptor, alpha, Interleukin3 receptor, Interleukin3 receptor, Y-chromosomal,IL3RA / CD123 (Acute Myeloid Leukemia Marker)
Cellular localisation: Cell surface and cytoplasm.

Molekulargewicht: ~70kDa

Gen-ID: 3563, 632790

UniProt: P26951

Pathways: JAK-STAT Signalweg