APOB Antikörper (AA 592-689)
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- Target Alle APOB Antikörper anzeigen
- APOB (Apolipoprotein B (APOB))
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Bindungsspezifität
- AA 592-689
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser APOB Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated byAPOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Human recombinant APOB protein fragment (around aa 592-689) (exact sequence is proprietary)
- Isotyp
- IgG1
- Top Product
- Discover our top product APOB Primärantikörper
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- Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Human liver or kidney tissue.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- APOB (Apolipoprotein B (APOB))
- Andere Bezeichnung
- APOB (APOB Produkte)
- Synonyme
- FLDB antikoerper, LDLCQ4 antikoerper, Ac1-060 antikoerper, Apo B-100 antikoerper, ApoB-100 antikoerper, ApoB-48 antikoerper, AI315052 antikoerper, apob-100 antikoerper, apob-48 antikoerper, APOB-100 antikoerper, ApoB(100) antikoerper, APOB antikoerper, apolipoprotein B antikoerper, APOB antikoerper, Apob antikoerper
- Hintergrund
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ApoB 100, ApoB 48, Apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, Apolipoprotein B, FLDB, LDLCQ4,Apolipoprotein B / APOB
Cellular localisation: Cytoplasm. Secreted. - Molekulargewicht
- 512kDa
- Gen-ID
- 338, 120759
- UniProt
- P04114
- Pathways
- Lipid Metabolism
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