WWP2 Antikörper
Kurzübersicht für WWP2 Antikörper (ABIN7120867)
Target
Alle WWP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- WWP2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- WW domain containing E3 ubiquitin protein ligase 2
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Isotyp
- IgG
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anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (Middle Region) antibody
WWP2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schaf WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 601-870) antibodyWWP2 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 1-335) antibodyWWP2 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (N-Term) antibodyWWP2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Affe, Hamster, Schwein WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (Middle Region) antibodyWWP2 Reaktivität: Human, Maus, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 151-400) antibodyWWP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 145-367) antibodyWWP2 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 218-252), (N-Term) antibodyWWP2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB51426 unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 1-110) antibodyWWP2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2) (AA 1-335) antibodyWWP2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- WB: 1:200-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
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Andere Bezeichnung
- WWP2
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Hintergrund
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Synonyms: NEDD4-like E3 ubiquitin-protein ligase WWP2|Atrophin-1-interacting protein 2 (AIP2)|HECT-type E3 ubiquitin transferase WWP2|WW domain-containing protein 2|WWP2
Background: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by 'Lys-63'-linked conjugation and promotes it to proteasomal degradation, in embryonic stem cells(ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation, in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2, the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
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Molekulargewicht
- 120 kDa
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Gen-ID
- 11060
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UniProt
- O00308
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Pathways
- Negative Regulation of Transporter Activity
Target
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