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WWP2 Antikörper (Middle Region)

WWP2 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schaf WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2774931
  • Target Alle WWP2 Antikörper anzeigen
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    Bindungsspezifität
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 32
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd, Schaf
    Wirt
    • 28
    • 4
    Kaninchen
    Klonalität
    • 31
    • 1
    Polyklonal
    Konjugat
    • 26
    • 2
    • 2
    • 2
    Dieser WWP2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 13
    • 8
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    EMKYTSEGVR YFVDHNTRTT TFKDPRPGFE SGTKQGSPGA YDRSFRWKYH
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Zebrafish: 80%
    Produktmerkmale
    This is a rabbit polyclonal antibody against WWP2. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human WWP2
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 431 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rougier, van Bemmelen, Bruce, Jespersen, Gavillet, Apothéloz, Cordonier, Staub, Rotin, Abriel: "Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins." in: American journal of physiology. Cell physiology, Vol. 288, Issue 3, pp. C692-701, (2005) (PubMed).

  • Target
    WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2 (WWP2))
    Andere Bezeichnung
    WWP2 (WWP2 Produkte)
    Synonyme
    aip2 antikoerper, wwp2-like antikoerper, id:ibd1121 antikoerper, wu:fo87e10 antikoerper, zgc:154036 antikoerper, AIP2 antikoerper, WWp2-like antikoerper, 1300010O06Rik antikoerper, AA690238 antikoerper, AW554328 antikoerper, WW domain containing E3 ubiquitin protein ligase 2 antikoerper, WWP2 antikoerper, wwp2 antikoerper, Wwp2 antikoerper
    Hintergrund
    WWP2 is a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. WWP2 contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions.This gene encodes a member of the NEDD4-like protein family. The family of proteins is known to possess ubiquitin-protein ligase activity. The encoded protein contains 4 tandem WW domains. The WW domain is a protein motif consisting of 35 to 40 amino acids and is characterized by 4 conserved aromatic residues. The WW domain may mediate specific protein-protein interactions. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alias Symbols: AIP2, WWp2-like
    Protein Interaction Partner: LGALS9B, ANKRD44, FBXL18, VPS37C, PABPC1, RUSC1, HNRNPUL1, WWP2, PAIP1, TRAF4, FAM189A2, PDLIM7, EIF3A, WIPF1, UBE2L3, UBC, SNRPC, PTCH1, SMAD6, SMAD3, EZH2, PTEN, UBE2D3, FBXL15, RNF11, ARRDC1, ARRDC4, ARRDC3, VPS11, UBE2G1, UBE2J2, UBE2E3, UBE2E1, UBE2D
    Protein Size: 431
    Molekulargewicht
    47 kDa
    Gen-ID
    11060
    NCBI Accession
    NM_199424, NP_955456
    UniProt
    O00308
    Pathways
    Negative Regulation of Transporter Activity
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