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TRIM24 Antikörper

TRIM24 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7120279
  • Target Alle TRIM24 Antikörper anzeigen
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Reaktivität
    • 59
    • 24
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 54
    • 6
    • 1
    Kaninchen
    Klonalität
    • 51
    • 10
    Polyklonal
    Konjugat
    • 40
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser TRIM24 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 21
    • 15
    • 9
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    tripartite motif-containing 24
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM24 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:5000, IP: 1:200-1:2000, IHC: 1:50-1:200, IF: 1:50-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    TRIM24 (Tripartite Motif Containing 24 (TRIM24))
    Andere Bezeichnung
    TRIM24 (TRIM24 Produkte)
    Hintergrund
    Synonyms:HTIF1, PTC6, RING finger protein 82, RNF82, TF1A, TIF1, TIF1 alpha, TIF1A, TIF1ALPHA, TRIM24, tripartite motif containing 24 Background:Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4'(H3K4me0) and acetylated at 'Lys-23'(H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor(TR) and ESR1. Modulates transcription activation by retinoic acid(RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes(By similarity).
    Molekulargewicht
    117 kDa
    Gen-ID
    8805
    UniProt
    O15164
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