TCF7L2 Antikörper
Kurzübersicht für TCF7L2 Antikörper (ABIN7120060)
Target
Alle TCF7L2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- transcription factor 7-like 2(T-cell specific, HMG-box)
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Isotyp
- IgG
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anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) antibody
TCF7L2 Reaktivität: Human, Maus, Ratte WB, IF (cc), IHC (p), IHC, FACS Wirt: Kaninchen Monoclonal 2C2 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 3A4 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 1B1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (N-Term) antibodyTCF7L2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1A1 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 61-90), (N-Term) antibodyTCF7L2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB19650 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 1-455) antibodyTCF7L2 Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1A9 unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (Middle Region) antibodyTCF7L2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen, Hund WB Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 401-550) antibodyTCF7L2 Reaktivität: Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) (AA 490-596) antibodyTCF7L2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Haltbarkeit
- 12 months
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- TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
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Andere Bezeichnung
- TCF7L2
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Hintergrund
- Synonyms:TCF4 Background:Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.
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Molekulargewicht
- 68 kDa
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Gen-ID
- 6934
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UniProt
- Q9NQB0
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Pathways
- WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
Target
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