STIM1 Antikörper
Kurzübersicht für STIM1 Antikörper (ABIN7119553)
Target
Alle STIM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- STIM1 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- stromal interaction molecule 1
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:200-1:2000 IHC: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- STIM1 (Stromal Interaction Molecule 1 (STIM1))
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Andere Bezeichnung
- STIM1
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Hintergrund
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Synonyms: Stromal interaction molecule 1|STIM1|GOK
Background: Plays a role in mediating store-operated Ca(2+) entry(SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores(By similarity). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+)(CRAC) channel subunit ORAI1(PubMed:16208375). Involved in enamel formation(By similarity). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch(By similarity).
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Molekulargewicht
- 77 kDa
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Gen-ID
- 6786
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UniProt
- Q13586
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Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
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