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RBX1 Antikörper

RBX1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7118665
  • Target Alle RBX1 Antikörper anzeigen
    RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
    Reaktivität
    • 42
    • 32
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 4
    Kaninchen
    Klonalität
    • 38
    • 4
    Polyklonal
    Konjugat
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RBX1 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 13
    • 13
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    ring-box 1
    Isotyp
    IgG
    Top Product
    Discover our top product RBX1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    RBX1 (Ring-Box 1, E3 Ubiquitin Protein Ligase (RBX1))
    Andere Bezeichnung
    RBX1 (RBX1 Produkte)
    Synonyme
    BA554C12.1 antikoerper, RNF75 antikoerper, ROC1 antikoerper, 1500002P15Rik antikoerper, AA517855 antikoerper, im:7137515 antikoerper, zgc:136444 antikoerper, RBX1 antikoerper, ATRBX1 antikoerper, F7C8.160 antikoerper, F7C8_160 antikoerper, HRT1 antikoerper, REGULATOR OF CULLINS-1 antikoerper, RING-BOX 1 antikoerper, RING-box 1 antikoerper, hop21 antikoerper, BEST:CK01110 antikoerper, CG16982 antikoerper, CK01110 antikoerper, Dmel\CG16982 antikoerper, EG:115C2.11 antikoerper, Rbx1 antikoerper, Rbx1/Roc antikoerper, Roc antikoerper, Roc1alpha antikoerper, anon-EST:Posey65 antikoerper, dRbx1 antikoerper, dRoc1 antikoerper, dRoc1a antikoerper, ring-box 1 antikoerper, ring-box 1, E3 ubiquitin protein ligase antikoerper, RING-box 1 antikoerper, RING-box protein 1 antikoerper, RING-box protein 1a antikoerper, Regulator of cullins 1a antikoerper, RBX1 antikoerper, Rbx1 antikoerper, rbx1 antikoerper, MGG_08844 antikoerper, LOC9308017 antikoerper, rbx-1 antikoerper, Roc1a antikoerper
    Hintergrund
    Synonyms:RNF75, ROC1 Background:E3 ubiquitin ligase component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins, including proteins involved in cell cycle progression, signal transduction, transcription and transcription-coupled nucleotide excision repair. The functional specificity of the E3 ubiquitin-protein ligase complexes depends on the variable substrate recognition components. As a component of the CSA complex promotes the ubiquitination of ERCC6 resulting in proteasomal degradation. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme, like CDC34, to the complex and brings it into close proximity to the substrate. Probably also stimulates CDC34 autoubiquitination. May be required for histone H3 and histone H4 ubiquitination in response to ultraviolet and for subsequent DNA repair. Promotes the neddylation of CUL1, CUL2, CUL4 and CUL4 via its interaction with UBE2M. Involved in the ubiquitination of KEAP1, ENC1 and KLHL41. In concert with ATF2 and CUL3, promotes degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM.
    Molekulargewicht
    12 kDa
    Gen-ID
    9978
    UniProt
    P62877
    Pathways
    Zellzyklus, M Phase, SARS-CoV-2 Protein Interaktom
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