RCC1 Antikörper

Produktnummer ABIN7118372

Der Kaninchen Polyklonal Anti-RCC1-Antikörper wurde für WB, ELISA, IHC, IF und IP validiert. Er ist geeignet, RCC1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für RCC1 Antikörper (ABIN7118372)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-RCC1 Antikörper

Verwendungszweck: RCC1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: regulator of chromosome condensation 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IP: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1

Hintergrund:

Synonyms: Regulator of chromosome condensation|Cell cycle regulatory protein|Chromosome condensation protein 1|RCC1|CHC1

Background: CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.

Molekulargewicht: 50 kDa

Gen-ID: 1104

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus