RCC1 Antikörper

Produktnummer ABIN6242601

Der Maus Monoklonal anti-RCC1 Antikörper wird verwendet zum Nachweis von RCC1 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für RCC1 Antikörper (ABIN6242601)

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RCC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 332CT2-1-1

Produktdetails anti-RCC1 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This RCC1 monoclonal antibody is generated from mouse immunized with RCC1 recombinant protein.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:100~250. WB: 1:2000-1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu RCC1

Target: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Andere Bezeichnung: RCC1

Hintergrund: Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.

Molekulargewicht: 44969

NCBI Accession: NP_001041659, NP_001041660, NP_001041664, NP_001260

UniProt: P18754

Pathways: Chromatin Binding, Protein targeting to Nucleus