RAC1 Antikörper

Produktnummer ABIN7118249

Der Maus Monoklonal anti-RAC1 Antikörper wird verwendet zum Nachweis von RAC1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC, IF und IP.

Kurzübersicht für RAC1 Antikörper (ABIN7118249)

Target: RAC1

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Klon: 5D9

Produktdetails anti-RAC1 Antikörper

Verwendungszweck: RAC1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ras-related C3 botulinum toxin substrate 1(rho family, small GTP binding protein Rac1)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:4000, IP: 1:200-1:2000, IHC: 1:50-1:500, IF: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RAC1

Target: RAC1

Hintergrund:

Synonyms: Ras-related C3 botulinum toxin substrate 1|Cell migration-inducing gene 5 protein|Ras-like protein TC25|p21-Rac1|RAC1|TC25

Background: RAC1b, also named as TC25, belongs to the small GTPase superfamily and Rho family. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, it binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles.

Molekulargewicht: 21 kDa

Gen-ID: 5879

UniProt: P63000

Pathways: WNT Signalweg, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling