PIAS4 Antikörper
Kurzübersicht für PIAS4 Antikörper (ABIN7117942)
Target
Alle PIAS4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PIAS4 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- protein inhibitor of activated STAT, 4
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Isotyp
- IgG
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anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 48-79), (N-Term) antibody
PIAS4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB0680 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibodyPIAS4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 471-499), (C-Term) antibodyPIAS4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB00682 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 60-260) antibodyPIAS4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 66-241) antibodyPIAS4 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-73), (N-Term) antibodyPIAS4 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB33956 unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 1-510) antibodyPIAS4 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (AA 44-60) antibodyPIAS4 Reaktivität: Human, Affe WB, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (N-Term) antibodyPIAS4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Affe, Fledermaus, Huhn, Schwein, Hamster, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibodyPIAS4 Reaktivität: Human, Rind (Kuh) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))
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Andere Bezeichnung
- PIAS4
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Hintergrund
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Synonyms: E3 SUMO-protein ligase PIAS4|PIASy|Protein inhibitor of activated STAT protein 4|Protein inhibitor of activated STAT protein gamma (PIAS-gamma)|PIAS4|PIASG
Background: Functions as an E3-type small ubiquitin-like modifier(SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.
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Molekulargewicht
- 60 kDa
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Gen-ID
- 51588
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UniProt
- Q8N2W9
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Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus
Target
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