Gastrin-Releasing Peptide Antikörper (AA 1-148)

Produktnummer ABIN7117775

Der Kaninchen Polyklonal Anti-Gastrin-Releasing Peptide-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, Gastrin-Releasing Peptide in Proben von Human zu detektieren.

Kurzübersicht für Gastrin-Releasing Peptide Antikörper (AA 1-148) (ABIN7117775)

Target: Gastrin-Releasing Peptide (GRP)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Gastrin-Releasing Peptide Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Gastrin-Releasing Peptide Antikörper

Bindungsspezifität: AA 1-148

Verwendungszweck: GRP antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-148aa

Immunogen: gastrin-releasing peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Gastrin-Releasing Peptide

Target: Gastrin-Releasing Peptide (GRP)

Andere Bezeichnung: GRP

Hintergrund:

Synonyms: Gastrin-releasing peptide (GRP)|Neuromedin-C Alternative names: GRP-10|GRP18-27|GRP

Background: Gastrin-releasing peptide, also known as GRP, is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, and its main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Its 148-amino acid preproprotein, following cleavage of a signal peptide, is further processed to produce either the 27-amino acid gastrin-releasing peptide or the 10-amino acid neuromedin C. These smaller peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation.These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate.

Molekulargewicht: 16 kDa, 32 kDa

Gen-ID: 2922

UniProt: P07492

Pathways: Peptide Hormone Metabolism, Hormone Activity