PRICKLE1 Antikörper

Produktnummer ABIN7117768

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PRICKLE1 in WB, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PRICKLE1 Antikörper (ABIN7117768)

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRICKLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-PRICKLE1 Antikörper

Verwendungszweck: PRICKLE1 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: prickle homolog 1(Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PRICKLE1

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Andere Bezeichnung: PRICKLE1

Hintergrund:

Synonyms: Prickle-like protein 1|REST/NRSF-interacting LIM domain protein 1|PRICKLE1|RILP

Background: Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor.

Molekulargewicht: 94 kDa, 55-60 kDa

Gen-ID: 144165

UniProt: Q96MT3

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus