PRICKLE1 Antikörper (C-Term)

Produktnummer ABIN1537540

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRICKLE1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PRICKLE1 Antikörper (C-Term) (ABIN1537540)

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRICKLE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB39636

Produktdetails anti-PRICKLE1 Antikörper

Bindungsspezifität: AA 678-704, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-704 amino acids from the C-terminal region of human PRICKLE1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PRICKLE1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PRICKLE1

Target: PRICKLE1 (Prickle-Like Protein 1 (PRICKLE1))

Andere Bezeichnung: PRICKLE1

Hintergrund: This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.

Molekulargewicht: 94300

Gen-ID: 144165

NCBI Accession: NP_001138353, NP_001138354, NP_001138355, NP_694571

UniProt: Q96MT3

Pathways: WNT Signalweg, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus