OCRL Antikörper
Kurzübersicht für OCRL Antikörper (ABIN7117103)
Target
Alle OCRL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- OCRL antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- oculocerebrorenal syndrome of Lowe
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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Andere Bezeichnung
- OCRL
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Hintergrund
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Synonyms: Inositol polyphosphate 5-phosphatase OCRL|Inositol polyphosphate 5-phosphatase OCRL-1 (OCRL-1)|Lowe oculocerebrorenal syndrome protein|Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase|OCRL|OCRL1
Background: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate(PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly(PubMed:22228094, PubMed:22543976).
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Molekulargewicht
- 105 kDa
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Gen-ID
- 4952
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UniProt
- Q01968
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Pathways
- Inositol Metabolic Process
Target
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