OCRL Antikörper (AA 146-240)
Kurzübersicht für OCRL Antikörper (AA 146-240) (ABIN782420)
Target
Alle OCRL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 146-240
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Spezifität
- This antibody reacts to OCRL.
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Aufreinigung
- Affinity chromatography on Protein A
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Immunogen
- OCRL antibody was raised against oCRL (NP_000267, 146 a.a. ~ 240 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1,0 mg/mL
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Buffer
- PBS, pH 7.2
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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Andere Bezeichnung
- OCRL
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Hintergrund
- RelevanceConverts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate. May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes.Synonyms: INPP5F, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein, OCRL-1, OCRL1
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Gen-ID
- 4952
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NCBI Accession
- NP_000267
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UniProt
- Q01968
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Pathways
- Inositol Metabolic Process
Target
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