OCRL Antikörper (C-Term)

Produktnummer ABIN6263797

Produktdetails anti-OCRL Antikörper

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OCRL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: OCRL Antibody detects endogenous levels of total OCRL.

Homologie: Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human OCRL, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: OCRL (OCRL Produkte)

Synonyme: OCRL antikoerper, wu:fi09g03 antikoerper, zgc:152864 antikoerper, locr antikoerper, nphl2 antikoerper, ocrl1 antikoerper, inpp5f antikoerper, INPP5F antikoerper, LOCR antikoerper, NPHL2 antikoerper, OCRL-1 antikoerper, OCRL1 antikoerper, 9530014D17Rik antikoerper, BB143339 antikoerper, OCRL, inositol polyphosphate-5-phosphatase antikoerper, phosphatidylinositol polyphosphate 5-phosphatase antikoerper, oculocerebrorenal syndrome of Lowe antikoerper, Ocrl antikoerper, NAEGRDRAFT_58601 antikoerper, OCRL antikoerper, ocrl antikoerper

Hintergrund:

Description: Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate (PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly (PubMed:22228094, PubMed:22543976).

Gene: OCRL

Molekulargewicht: 104 kDa

Gen-ID: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process