OCRL Antikörper (Internal Region)

Produktnummer ABIN7216158

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch OCRL in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für OCRL Antikörper (Internal Region) (ABIN7216158)

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OCRL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-OCRL Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-OCRL Polyclonal Antibody

Spezifität: OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human OCRL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Andere Bezeichnung: OCRL

Hintergrund: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome proteinOCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 104kD

Gen-ID: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process