Dieses Anti-NOTCH3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NOTCH3 in WB, ELISA, IHC und IP. Geeignet für Human, Maus und Ratte.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
NOTCH3
(Notch 3 (NOTCH3))
Andere Bezeichnung
NOTCH3
Hintergrund
Synonyms:CADASIL, CASIL, Notch 3, Notch homolog 3, NOTCH3 Background:Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity).