Cytokeratin 18 Antikörper (AA 127-430)

Produktnummer ABIN7115628

Dieses Anti-Cytokeratin 18-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Cytokeratin 18 in WB, IHC, IF, FACS und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Cytokeratin 18 Antikörper (AA 127-430) (ABIN7115628)

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 18 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), ELISA

Klon: 6E3

Produktdetails anti-Cytokeratin 18 Antikörper

Bindungsspezifität: AA 127-430

Verwendungszweck: KRT18 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 127-430aa

Immunogen: keratin 18

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:5000-1:30000, IHC: 1:500-1:1000, IF: 1:100-1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Cytokeratin 18

Target: Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung: KRT18

Hintergrund:

Synonyms: Keratin, type I cytoskeletal 18|Cell proliferation-inducing gene 46 protein|Cytokeratin-18 (CK-18)|Keratin-18 (K18)|KRT18|CYK18

Background: Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9-K23, and the hair keratins Ha1-Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1-K8, and the hair keratins, Hb1-Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.

Molekulargewicht: 48 kDa

Gen-ID: 3875

UniProt: P05783

Pathways: Apoptose, Caspase Kaskade in der Apoptose