IDH1 Antikörper (AA 120-414)
Kurzübersicht für IDH1 Antikörper (AA 120-414) (ABIN7115525)
Target
Alle IDH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 120-414
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Verwendungszweck
- IDH1 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 120-414aa
Immunogen: isocitrate dehydrogenase 1(NADP+), soluble
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
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Andere Bezeichnung
- IDH1
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Hintergrund
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Synonyms: Isocitrate dehydrogenase [NADP] cytoplasmic (IDH, IDH1)|Cytosolic NADP-isocitrate dehydrogenase|IDPc|NADP(+)-specific ICDH|Oxalosuccinate decarboxylase|IDH1|PICD
Background: IDH1, also named as PICD and IDP, belongs to the isocitrate and isopropylmalate dehydrogenases family. It is a common feature of a major subset of primary human brain cancers. It can form a homodimer(PMID:15173171).IDH1 mutation is always heterozygotic and IDH1 functions as a dimer, theoretically there will be 25 % each wild type and mutant homo-dimers and 50 % hetero-dimers present in the tumor cells(PMID:21079649 ).
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Molekulargewicht
- 46 kDa
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Gen-ID
- 3417
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UniProt
- O75874
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Pathways
- Warburg Effekt
Target
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