IDH1 Antikörper (AA 116-143)
Kurzübersicht für IDH1 Antikörper (AA 116-143) (ABIN3031506)
Target
Alle IDH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 116-143
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Verwendungszweck
- IDH1 Antibody
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Kreuzreaktivität (Details)
- Expected species reactivity: Rat, Bovine
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 116-143 from the human protein was used as the immunogen for this IDH1 antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the IDH1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the IDH1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IDH1 (Isocitrate Dehydrogenase 1 (NADP+), Soluble (IDH1))
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Andere Bezeichnung
- IDH1
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Hintergrund
- IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent Isocitrate Dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. [Wiki]
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UniProt
- O75874
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Pathways
- Warburg Effekt
Target
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