IFT57 Antikörper
Kurzübersicht für IFT57 Antikörper (ABIN7115495)
Target
Alle IFT57 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- IFT57 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- intraflagellar transport 57 homolog(Chlamydomonas)
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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Andere Bezeichnung
- IFT57
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Hintergrund
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Synonyms: Intraflagellar transport protein 57 homolog|Dermal papilla-derived protein 8|Estrogen-related receptor beta-like protein 1|HIP1-interacting protein|MHS4R2|IFT57|DERP8|ESRRBL1|HIPPI
Background: Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
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Molekulargewicht
- 49 kDa
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Gen-ID
- 55081
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UniProt
- Q9NWB7
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Pathways
- Hedgehog Signalweg, Positive Regulation of Endopeptidase Activity
Target
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