IFT57 Antikörper (AA 159-193)
Kurzübersicht für IFT57 Antikörper (AA 159-193) (ABIN6243690)
Target
Alle IFT57 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 159-193
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Homologie
- B
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This IFT57 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-193 amino acids from the Central region of human IFT57.
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Isotyp
- Ig Fraction
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anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibody
IFT57 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1G8 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 1-429) antibodyIFT57 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyIFT57 Reaktivität: Human, Maus, Ratte, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 170-429) antibodyIFT57 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyVerified IFT57 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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Andere Bezeichnung
- IFT57
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Hintergrund
- Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro- apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
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Molekulargewicht
- 49108
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UniProt
- Q9NWB7
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Pathways
- Hedgehog Signalweg, Positive Regulation of Endopeptidase Activity
Target
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