Fibronectin 1 Antikörper (AA 2268-2477)

Produktnummer ABIN7114225

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Fibronectin 1 in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Fibronectin 1 Antikörper (AA 2268-2477) (ABIN7114225)

Target: Fibronectin 1 (FN1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibronectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Klon: 3G6

Produktdetails anti-Fibronectin 1 Antikörper

Bindungsspezifität: AA 2268-2477

Verwendungszweck: FN1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 2268-2477aa

Immunogen: fibronectin 1

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:10000, IHC: 1:300-1:1000, IF: 1:50-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu Fibronectin 1

Target: Fibronectin 1 (FN1)

Andere Bezeichnung: FN1

Hintergrund:

Synonyms: Fibronectin (FN)|Cold-insoluble globulin (CIG)|Anastellin|Ugl-Y1|Ugl-Y2|Ugl-Y3|FN1|FN

Background: Fibronectin 1(FN1) is a high molecular weight glycoprotein which exists in both a soluble form in plasma(plasma FN1) and other body fluids and an insoluble form in the extracellular matrix(cellular FN1). Plasma FN1(dimeric form) is secreted by hepatocytes. Cellular FN(dimeric or cross-linked multimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellular matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis.(PMID: 7276612, 12244123, 12847088)

Molekulargewicht: 260 kDa

Gen-ID: 2335

UniProt: P02751

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie