FRS2 Antikörper
Kurzübersicht für FRS2 Antikörper (ABIN7114220)
Target
Alle FRS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- FRS2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- fibroblast growth factor receptor substrate 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
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Andere Bezeichnung
- FRS2
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Hintergrund
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Synonyms: Fibroblast growth factor receptor substrate 2 (FGFR substrate 2)|FGFR-signaling adaptor SNT|Suc1-associated neurotrophic factor target 1 (SNT-1)|FRS2
Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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Molekulargewicht
- 60 kDa
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Gen-ID
- 10818
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UniProt
- Q8WU20
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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