FRS2 Antikörper (Tyr196)

Produktnummer ABIN7180012

Produktdetails anti-FRS2 Antikörper

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Bindungsspezifität: Tyr196

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized non-phosphopeptide derived from Human FRS2 around the phosphorylation site of tyrosine 196 (H-T-Y(p)-V-N).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FRS2

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Andere Bezeichnung: FRS2 (FRS2 Produkte)

Synonyme: frs2 antikoerper, wu:fd21h10 antikoerper, zgc:91973 antikoerper, FRS2A antikoerper, FRS2alpha antikoerper, SNT antikoerper, SNT-1 antikoerper, SNT1 antikoerper, 4732458E18 antikoerper, C330018A15Rik antikoerper, Frs2alpha antikoerper, fibroblast growth factor receptor substrate 2 antikoerper, fibroblast growth factor receptor substrate 2b antikoerper, FRS2 antikoerper, frs2b antikoerper, Frs2 antikoerper

Hintergrund:

Background: Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

The MGC Project Team, Genome Res. 14:2121-2127(2004).
Xu H., J. Biol. Chem. 273:17987-17990(1998).
Meakin S.O., J. Biol. Chem. 274:9861-9870(1999).

Aliases: FGFR signaling adaptor SNT antibody, FGFR signalling adaptor antibody, FGFR substrate 2 antibody, FGFR-signaling adaptor SNT antibody, Fibroblast growth factor receptor substrate 2 antibody, FRS 2 antibody, FRS2 antibody, FRS2_HUMAN antibody, FRS2A antibody, FRS2alpha antibody, SNT 1 antibody, SNT antibody, SNT-1 antibody, SNT1 antibody, Suc 1 Associated Neurotrophic Factor Target antibody, Suc1 associated neurotrophic factor target 1 antibody, Suc1-associated neurotrophic factor target 1 antibody

UniProt: Q8WU20

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Signaling Events mediated by VEGFR1 and VEGFR2