FRS2 Antikörper (pTyr436)

Produktnummer ABIN1532103

Produktdetails anti-FRS2 Antikörper

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Bindungsspezifität: AA 402-451, pTyr436

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FRS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität:

FRS2 (Phospho-Tyr436) Antibody detects endogenous levels of FRS2 only when phosphorylated at Tyr436.

PhosphorylationH:Y436 M:Y436

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human FRS2 around the phosphorylation site of Tyr436.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Kommentare:

Unigene-Number: Hs.593446 (NCBI Gene Symbol: FRS2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-FRS2 Antikörper (ABIN1532103)

Sun, Zou, Yang, Morita, Gong, Shiba, Akagawa, Yuan: "Inorganic polyphosphates stimulate FGF23 expression through the FGFR pathway." in: Biochemical and biophysical research communications, Vol. 428, Issue 2, pp. 298-302, (2012) (PubMed).

Details zu FRS2

Target: FRS2 (Fibroblast Growth Factor Receptor Substrate 2 (FRS2))

Andere Bezeichnung: FRS2 (FRS2 Produkte)

Synonyme: frs2 antikoerper, wu:fd21h10 antikoerper, zgc:91973 antikoerper, FRS2A antikoerper, FRS2alpha antikoerper, SNT antikoerper, SNT-1 antikoerper, SNT1 antikoerper, 4732458E18 antikoerper, C330018A15Rik antikoerper, Frs2alpha antikoerper, fibroblast growth factor receptor substrate 2 antikoerper, fibroblast growth factor receptor substrate 2b antikoerper, FRS2 antikoerper, frs2b antikoerper, Frs2 antikoerper

Hintergrund:

Synonyms: FGFR signalling adaptor, FGFR signalling adaptor SNT-1, SNT-1, SNT2, SUC1-associated neurotrophic factor target, Suc1-associated neurotrophic factor target

NCBI Gene Symbol: FRS2

Molekulargewicht: 57 kDa

Gen-ID: 10818

OMIM: 607743

UniProt: Q8WU20

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Signaling Events mediated by VEGFR1 and VEGFR2