Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 1-374) Antikörper

Produktnummer ABIN7113959

Der Maus Monoklonal Anti--Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M) (AA 1-374) Antikörper (ABIN7113959)

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Klon: 1A4

Produktdetails

Bindungsspezifität: AA 1-374

Verwendungszweck: EIF3M antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-374aa

Immunogen: eukaryotic translation initiation factor 3, subunit M

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: Eukaryotic Translation Initiation Factor 3, Subunit M (EIF3M)

Andere Bezeichnung: EIF3M

Hintergrund:

Synonyms: Eukaryotic translation initiation factor 3 subunit M (eIF3m)|Fetal lung protein B5 (hFL-B5)|PCI domain-containing protein 1|EIF3M|HFLB5|PCID1

Background: Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1(HSV1) or herpes simplex virus 2(HSV2).

Molekulargewicht: 43 kDa

Gen-ID: 10480

UniProt: Q7L2H7

Pathways: Ribonucleoprotein Complex Subunit Organization