DLL4 Antikörper
Kurzübersicht für DLL4 Antikörper (ABIN7113410)
Target
Alle DLL4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- DLL4 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- delta-like 4(Drosophila)
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:2000, IP: 1:200-1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- DLL4 (delta-Like 4 (DLL4))
-
Andere Bezeichnung
- DLL4
-
Hintergrund
-
Synonyms: Delta-like protein 4|Drosophila Delta homolog 4 (Delta4)|DLL4
Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
-
Molekulargewicht
- 75-80 kDa
-
Gen-ID
- 54567
-
UniProt
- Q9NR61
-
Pathways
- Notch Signalweg
Target
-