beta Catenin Antikörper

Produktnummer ABIN7112390

Der Maus Monoklonal Anti-beta Catenin-Antikörper wurde für WB, IHC, IF, ELISA und IP validiert. Er ist geeignet, beta Catenin in Proben von Human, Maus, Ratte und Schwein zu detektieren.

Kurzübersicht für beta Catenin Antikörper (ABIN7112390)

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta Catenin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Klon: 5D7

Produktdetails anti-beta Catenin Antikörper

Aufreinigung: protein A+G purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: catenin(cadherin-associated protein), beta 1, 88kDa

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:2000-1:20000, IP: 1:1000-1:5000, IHC: 1:200-1:1000, IF: 1:20-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu beta Catenin

Target: beta Catenin (CATNB) (Catenin, beta (CATNB))

Andere Bezeichnung: beta-Catenin

Hintergrund: Synonyms:b cat, Beta catenin, beta-Catenin, Catenin beta 1, CTNNB, CTNNB1, PRO2286, β catenin, β-catenin Background:The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 90 kDa

Gen-ID: 1499

UniProt: P35222

Pathways: Peptide Hormone Metabolism