CRADD Antikörper
Kurzübersicht für CRADD Antikörper (ABIN7112351)
Target
Alle CRADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- CRADD antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- CASP2 and RIPK1 domain containing adaptor with death domain
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Isotyp
- IgG
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anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibody
CRADD Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1F8 unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyKD Validated CRADD Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 25GB3380 unconjugated Recombinant Antibody
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) antibodyCRADD Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD Reaktivität: Human WB, ELISA, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD Reaktivität: Human WB, ELISA, ICC, IF Wirt: Maus Monoclonal AT14G8 unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 99-117), (Middle Region) antibodyCRADD Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
anti-CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (AA 1-199) antibodyCRADD Reaktivität: Human ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IP: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
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Andere Bezeichnung
- CRADD
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Hintergrund
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Synonyms: Death domain-containing protein CRADD|Caspase and RIP adapter with death domain|RIP-associated protein with a death domain|CRADD|RAIDD
Background: RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses.
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Molekulargewicht
- 23 kDa
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UniProt
- P78560
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
Target
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