Der Maus Monoklonal Anti-BMI1-Antikörper wurde für WB, IHC, ELISA, IF und IP validiert. Er ist geeignet, BMI1 in Proben von Human und Maus zu detektieren.
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Haltbarkeit
12 months
Target
BMI1
(BMI1 Polycomb Ring Finger Oncogene (BMI1))
Andere Bezeichnung
BMI1
Hintergrund
Synonyms:BMI1, PCGF4, Polycomb complex protein BMI 1, RING finger protein 51, RNF51 Background:Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.