alpha 2 Macroglobulin Antikörper (AA 1100-1474)

Produktnummer ABIN7111503

Dieses Anti-alpha 2 Macroglobulin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von alpha 2 Macroglobulin in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für alpha 2 Macroglobulin Antikörper (AA 1100-1474) (ABIN7111503)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon: 6D0

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Bindungsspezifität: AA 1100-1474

Verwendungszweck: A2M antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1100-1474aa

Immunogen: alpha-2-macroglobulin

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:50-1:500, IHC: 1:20-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: A2M

Hintergrund:

Synonyms: Alpha-2-macroglobulin (Alpha-2-M)|C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5|A2M|CPAMD5

Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer's disease.

Molekulargewicht: 185 kDa

Gen-ID: 2

UniProt: P01023

Pathways: Lipid Metabolism