Adenylosuccinate Lyase Antikörper

Produktnummer ABIN7111349

Der Kaninchen Polyklonal Anti-Adenylosuccinate Lyase-Antikörper wurde für WB, IHC, ELISA, IF und FACS validiert. Er ist geeignet, Adenylosuccinate Lyase in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Adenylosuccinate Lyase Antikörper (ABIN7111349)

Target: Adenylosuccinate Lyase (ADSL)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylosuccinate Lyase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Adenylosuccinate Lyase Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: adenylosuccinate lyase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Andere Bezeichnung: Adenylosuccinate lyase

Hintergrund: Synonyms:Adenylosuccinase, adenylosuccinate lyase, ADSL, AMPS, ASASE, ASL Background:ADSL(adenylosuccinate lyase) is also named as AMPS, ASase, ASL and belongs to the lyase 1 family. It is an enzyme involved in 2 pathways of purine nucleotide metabolism and catalyzes cleavage of succinyl groups to yield fumarate(PMID:18524658). Defects in ADSL are the cause of adenylosuccinase deficiency(ADSL deficiency). In humans, mutations in ADSL lead to an inborn error of metabolism originally characterized by developmental delay, often with autistic features(PMID:20884265)..The ADSL enzymatic activity is reduced in lymphocytes and red blood cells of the patient with severe psychomotor retardation(PMID:9545543). It has 2 isoforms produced by alternative splicing.

Molekulargewicht: 55 kDa

Gen-ID: 158

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process