Adenylosuccinate Lyase Antikörper (Middle Region)

Produktnummer ABIN2774275

Produktdetails anti-Adenylosuccinate Lyase Antikörper

Target: Adenylosuccinate Lyase (ADSL)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylosuccinate Lyase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RVRDDLRFRG VKGTTGTQAS FLQLFEGDDH KVEQLDKMVT EKAGFKRAFI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ADSL. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ADSL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 484 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Andere Bezeichnung: ADSL (ADSL Produkte)

Synonyme: fi60b04 antikoerper, zgc:56061 antikoerper, wu:fi60b04 antikoerper, MGC53383 antikoerper, MGC69239 antikoerper, adsL antikoerper, F15C21.8 antikoerper, F15C21_8 antikoerper, AMPS antikoerper, ASASE antikoerper, ASL antikoerper, Adl antikoerper, Asl antikoerper, purB antikoerper, adenylosuccinate lyase antikoerper, adenylosuccinate lyase L homeolog antikoerper, adenylosuccinase; ASL antikoerper, Adenylosuccinate lyase antikoerper, L-Aspartase-like family protein antikoerper, ADSL antikoerper, adsl antikoerper, adsl.L antikoerper, ASL antikoerper, purB antikoerper, purB,adsL antikoerper, Mrub_2293 antikoerper, MMAH_RS02975 antikoerper, Arnit_0089 antikoerper, Mesil_1058 antikoerper, Slip_0597 antikoerper, Trad_2452 antikoerper, Deba_0652 antikoerper, Toce_1174 antikoerper, Acear_2324 antikoerper, Igag_0272 antikoerper, Saut_2156 antikoerper, Fbal_1996 antikoerper, Ndas_2434 antikoerper, Ilyop_0196 antikoerper, Lbys_2961 antikoerper, MFER_RS02920 antikoerper, Palpr_2192 antikoerper, Calni_0061 antikoerper, Ftrac_3746 antikoerper, AT1G36280 antikoerper, Olsu_1764 antikoerper, Adsl antikoerper

Hintergrund: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMPS, ASASE, ASL
Protein Interaction Partner: CALCOCO2, REL, UBC, PDE12, BTF3L4, NPLOC4, EHD4, UBQLN2, NT5C2, WDR4, PAIP1, PLIN3, SAE1, OXSR1, API5, XPNPEP1, WARS, RAD23B, TWF1, DNAJB1, GTF2I, EIF1AX, DRG2, CTSC, NOV, TYMS, SUMO1, DDA1, USP15, USP4,
Protein Size: 484

Molekulargewicht: 55 kDa

Gen-ID: 158

NCBI Accession: NM_000026, NP_000017

UniProt: P30566

Pathways: Ribonucleoside Biosynthetic Process