ACO2 Antikörper (AA 51-246)
Kurzübersicht für ACO2 Antikörper (AA 51-246) (ABIN7111197)
Target
Alle ACO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 51-246
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Verwendungszweck
- ACO2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 51-246aa
Immunogen: aconitase 2, mitochondrial
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ACO2 (Aconitase 2, Mitochondrial (ACO2))
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Andere Bezeichnung
- ACO2
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Hintergrund
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Synonyms: Aconitate hydratase, mitochondrial (Aconitase)|Citrate hydro-lyase|ACO2
Background: ACO2(aconitate hydratase, mitochondrial) is also named as citrate hydro-lyase and belongs to the aconitase/IPM isomerase family. It plays a key function in cellular energy production, and loss of its activity has a major impact on cellular and organismal survival. Western blot shows two bands of 83 kDa and 40 kDa. The 40 kDa fragment decreases with age and oxidative stress, whereas other fragmentation products with molecular weights between 40 and 83 kDa increased with age and MnSOD(mitochondrial manganese superoxide dismutase) deficiency(PMID:12459471). Defects in ACO2 are the cause of infantile cerebellar-retinal degeneration(ICRD).
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Molekulargewicht
- 85 kDa
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Gen-ID
- 50
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UniProt
- Q99798
Target
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