CTLA4 Antikörper (AA 36-161) (Biotin)

Produktnummer ABIN7092999

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch CTLA4 in FACS und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CTLA4 Antikörper (AA 36-161) (Biotin) (ABIN7092999)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), ELISA

Klon: DM50

Produktdetails anti-CTLA4 Antikörper (Biotin)

Bindungsspezifität: AA 36-161

Verwendungszweck: Biotinylated Anti-CTLA4 antibody(DM50), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human  CTLA4(Gln36-Ser161) (ABIN6961090) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:5000-10000, Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA-4

Hintergrund: Synonyms:CTLA4, CD152
Description:Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Molekulargewicht: 24.6 kDa

Gen-ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints