IL3RA Antikörper (AA 19-305) (Biotin)

Produktnummer ABIN7092989

Der Biotin-konjugierte Kaninchen Monoklonal anti-IL3RA Antikörper (Klon DM31) (ABIN7092989) detektiert spezifisch IL3RA in FACS und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IL3RA Antikörper (AA 19-305) (Biotin) (ABIN7092989)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), ELISA

Klon: DM31

Produktdetails anti-IL3RA Antikörper (Biotin)

Bindungsspezifität: AA 19-305

Verwendungszweck: Biotinylated Anti-CD123 antibody(DM31), Rabbit mAb

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human  CD123(Thr19-Arg305) (ABIN6961076) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:5000-10000, Flow Cyt 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: CD123

Hintergrund: Synonyms:IL3R, IL3RA, IL-3Ra, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, CD123 antigen, CD123, hIL3Ra, hIL-3Ra, MGC34174, IL-3 R alpha
Description:Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

Molekulargewicht: 39kDa

Gen-ID: 3563

UniProt: P26951

Pathways: JAK-STAT Signalweg