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EGFR Antikörper (AA 25-645)

Dieses Anti-EGFR-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von EGFR in ELISA und FACS. Geeignet für Human.
Produktnummer ABIN7092929

Kurzübersicht für EGFR Antikörper (AA 25-645) (ABIN7092929)

Target

Alle EGFR Antikörper anzeigen
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reaktivität

  • 817
  • 298
  • 287
  • 25
  • 25
  • 24
  • 20
  • 14
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 591
  • 225
  • 14
  • 13
  • 5
  • 3
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 535
  • 314
  • 2
Monoklonal

Konjugat

  • 433
  • 64
  • 28
  • 21
  • 18
  • 18
  • 18
  • 17
  • 16
  • 16
  • 16
  • 13
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 2
  • 1
  • 1
  • 1
Dieser EGFR Antikörper ist unkonjugiert

Applikation

  • 582
  • 252
  • 184
  • 159
  • 141
  • 109
  • 102
  • 93
  • 82
  • 64
  • 37
  • 34
  • 33
  • 22
  • 19
  • 11
  • 8
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Flow Cytometry (FACS)

Klon

DM128
  • Bindungsspezifität

    • 41
    • 40
    • 31
    • 31
    • 29
    • 28
    • 27
    • 27
    • 26
    • 22
    • 22
    • 18
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 13
    • 12
    • 12
    • 11
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    AA 25-645

    Aufreinigung

    Purified from cell culture supernatant by affinity chromatography

    Immunogen

    Recombinant human EGFR(Leu25-Ser645) (ABIN6964078) produced by using human HEK293 cells

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1/5000-10000,Flow Cyt  1/100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute with deionized water

    Buffer

    Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

    Haltbarkeit

    12 months
  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Andere Bezeichnung

    EGFR

    Hintergrund

    Synonyms:EGFR,ERBB,ERBB1,HER1,PIG61,mENA
    Description:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

    Molekulargewicht

    69.4 kDa

    Gen-ID

    1956

    UniProt

    P00533

    Pathways

    NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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