EGFR Antikörper (AA 25-645)
Kurzübersicht für EGFR Antikörper (AA 25-645) (ABIN7092929)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 25-645
-
Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
-
Immunogen
- Recombinant human EGFR(Leu25-Ser645) (ABIN6964078) produced by using human HEK293 cells
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- ELISA 1/5000-10000,Flow Cyt 1/100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Reconstitute with deionized water
-
Buffer
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
-
Haltbarkeit
- 12 months
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
Andere Bezeichnung
- EGFR
-
Hintergrund
-
Synonyms:EGFR,ERBB,ERBB1,HER1,PIG61,mENA
Description:The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. -
Molekulargewicht
- 69.4 kDa
-
Gen-ID
- 1956
-
UniProt
- P00533
-
Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
-