CSF1R Antikörper (AA 20-514)

Produktnummer ABIN7092907

Der Kaninchen Monoklonal Anti-CSF1R-Antikörper wurde für ELISA und FACS validiert. Er ist geeignet, CSF1R in Proben von Human zu detektieren.

Kurzübersicht für CSF1R Antikörper (AA 20-514) (ABIN7092907)

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CSF1R Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Klon: DM106

Produktdetails anti-CSF1R Antikörper

Bindungsspezifität: AA 20-514

Aufreinigung: Purified from cell culture supernatant by affinity chromatography

Immunogen: Recombinant human CSF1R (Ile20-Leu514) (ABIN6961125) produced by using human HEK293 cells

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1/5000-10000,Flow Cyt  1/100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.,0.1 % Procline 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Haltbarkeit: 12 months

Details zu CSF1R

Target: CSF1R (Colony Stimulating Factor 1 Receptor (CSF1R))

Andere Bezeichnung: CSF1R

Hintergrund: Synonyms:CSF1R,C-FMS,CD115,CSFR,FIM2,FMS,M-CSFR
Description:The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

Molekulargewicht: 55.6 kDa

Gen-ID: 1436

UniProt: P07333

Pathways: RTK Signalweg, Inositol Metabolic Process, Cell-Cell Junction Organization